Meta-analysis of Theory of Mind (ToM) impairment in bipolar disorder
E Bora, C Bartholomeusz, C Pantelis
PSYCHOLOGICAL MEDICINE | CAMBRIDGE UNIV PRESS | Published : 2016
BACKGROUND: Theory of mind (ToM) dysfunction is prominent in a number of psychiatric disorders, in particular, autism and schizophrenia, and can play a significant role in poor functioning. There is now emerging evidence suggesting that ToM abilities are also impaired in bipolar disorder (BP); however, the relationship between ToM deficits and mood state is not clear. METHOD: We conducted a meta-analysis of ToM studies in BP. Thirty-four studies comparing 1214 patients with BP and 1097 healthy controls were included. BP groups included remitted (18 samples, 545 BP patients), subsyndromal (12 samples, 510 BP patients), and acute (manic and/or depressed) (10 samples, 159 BP patients) patients...View full abstract
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Awarded by NHMRC
Prof Christos Pantelis was supported by a NHMRC Senior Principal Research Fellowship (ID 628386).