An integrated Java tool for generating amino acid sequence alignments with mapped secondary structure elements
Conan K Wang, Andreas Hofmann
3 BIOTECH | SPRINGER HEIDELBERG | Published : 2015
The mapping of secondary structure elements onto amino acid sequences enhances the quality of alignments frequently used in phylogenetic, genomic and transcriptomic studies, as well as in molecular modelling. Here, we report recent updates to the Java application SBAL, an integrated tool to generate, edit, visualise and analyse secondary structure-based sequence alignments. The main goal of the software is to streamline the work flow in generation of structure-based alignments, and we have thus implemented the option to import and visualise sequence and structure information directly from any PDB file. The new feature is achieved by a Java application named ASSP which follows the original fr..View full abstract
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Awarded by National Health and Medical Research Council
Awarded by Australian Research Council
Research in the laboratory of AH is funded by the National Health and Medical Research Council (APP1002898, APP1044022) and the Australian Research Council (DP140100599, LE120100071, LP120100485).