The Patient Remote Intervention and Symptom Management System (PRISMS) - a Telehealth-mediated intervention enabling real-time monitoring of chemotherapy side-effects in patients with haematological malignancies: study protocol for a randomised controlled trial
Sibilah Breen, David Ritchie, Penelope Schofield, Ya-seng Hsueh, Karla Gough, Nick Santamaria, Rose Kamateros, Roma Maguire, Nora Kearney, Sanchia Aranda
TRIALS | BMC | Published : 2015
BACKGROUND: Outpatient chemotherapy is a core treatment for haematological malignancies; however, its toxicities frequently lead to distressing/potentially life-threatening side-effects (neutropenia/infection, nausea/vomiting, mucositis, constipation/diarrhoea, fatigue). Early detection/management of side-effects is vital to improve patient outcomes, decrease morbidity and limit lengthy/costly hospital admissions. The ability to capture patient-reported health data in real-time, is regarded as the 'gold-standard' to allow rapid clinical decision-making/intervention. This paper presents the protocol for a Phase 3 multi-site randomised controlled trial evaluating a novel nurse-led Telehealth i..View full abstract
This trial is financially supported by a grant from the National Health and Medical Research Council. The authors would also like to acknowledge the input from Ms Tracey Dryden for her work on developing and testing the prototype remote monitoring system, and in assisting with the development of nurse training materials; Mr Clem Byard for assistance with development of nurse training materials and his invaluable assistance with organising and completing numerous nurse training sessions; Aridhia Informatics Limited for the programming and testing of the patient remote monitoring system; Ms Sharna Debnam for her invaluable assistance in identifying patient approach strategies and Ms Clare Coulson for providing feedback and assistance with the final draft of this manuscript. Also a huge 'thank you' to the patients and nurses who have given so much of their time to participate in this trial.