AZITHROMYCIN VERSUS DOXYCYCLINE FOR THE TREATMENT OF GENITAL CHLAMYDIA INFECTION - A META-ANALYSIS OF RANDOMISED CONTROLLED TRIALS

Abstract

IntroductionThere has been considerable debate questioning the efficacy of azithromycin for the treatment of genital chlamydia. We conducted a meta-analysis to compare the efficacy of 1 gramme azithromycin with 100mg doxycycline twice daily for seven days for the treatment of genital chlamydia infection.MethodsMedline, PubMed, Embase and the Cochrane Controlled Trials Register were searched till end 2012. Inclusion criteria included (1) randomised controlled trial of azithromycin versus doxycycline for the treatment of urethral or cervical chlamydia, and; (2) evaluation of microbial cure within 3 months of treatment. Type of diagnostic test, duration of follow up, gender, patient status (all..