Substantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species Infection

Xing Yu; Rahul Mishra; Gavan Holloway; Mark von Itzstein; Barbara S Coulson; Helen Blanchard

Journal article

Substantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species Infection

Xing Yu, Rahul Mishra, Gavan Holloway, Mark von Itzstein, Barbara S Coulson, Helen Blanchard

ChemBioChem | WILEY-V C H VERLAG GMBH | Published : 2015

DOI: 10.1002/cbic.201500360

University of Melbourne Researchers

Barbara Coulson Author Microbiology and Immunology

Related Projects (1)

NEW INSIGHT INTO GLYCAN REQUIREMENTS FOR ROTAVIRUS-CELL ATTACHMENT AND ENTRY

Rotavirus causes significant infection and loss of life in children, particularly in underdeveloped countries. This project will investigate..

Grants

Awarded by National Health and Medical Research Council of Australia

Awarded by NHMRC

Funding Acknowledgements

Financial support from the National Health and Medical Research Council of Australia (ID1085596 to H.B., B.S.C., and M.v.I.) is gratefully acknowledged. B.S.C. is a Senior Research Fellow of the NHMRC (ID628319). The authors acknowledge Vi Dang for her assistance in VP8* plasmid production and the MX1 and MX2 beamline scientists at the Australian Synchrotron for their support during X-ray diffraction data collection.