Immunosurveillance and therapy of multiple myeloma are CD226 dependent

Camille Guillerey; Lucas Ferrari de Andrade; Slavica Vuckovic; Kim Miles; Shin Foong Ngiow; Michelle CR Yong; Michele WL Teng; Marco Colonna; David S Ritchie; Martha Chesi; P Leif Bergsagel; Geoffrey R Hil; Mark J Smyth; Ludovic Martinet

Journal article

Immunosurveillance and therapy of multiple myeloma are CD226 dependent

Camille Guillerey, Lucas Ferrari de Andrade, Slavica Vuckovic, Kim Miles, Shin Foong Ngiow, Michelle CR Yong, Michele WL Teng, Marco Colonna, David S Ritchie, Martha Chesi, P Leif Bergsagel, Geoffrey R Hil, Mark J Smyth, Ludovic Martinet

Journal of Clinical Investigation | AMER SOC CLINICAL INVESTIGATION INC | Published : 2015

DOI: 10.1172/JCI77181

University of Melbourne Researchers

David Ritchie Author Medicine - Royal Melbourne Hospital

Related Projects (2)

IMMUNE REGULATION EFFECTOR FUNCTION AND THERAPY

We seek to understand how white blood cells detect and destroy disease, and how molecules of the immune system punch holes in diseased cells..

IMMUNE REGULATION EFFECTOR FUNCTION AND THERAPY

We seek to understand how white blood cells detect and destroy disease, and how molecules of the immune system punch holes in diseased cells..

Grants

Awarded by National Health and Medical Research Council (NH&MRC) of Australia

Awarded by NHMRC Australia

Awarded by ARC cancer research foundation

Awarded by NATIONAL CANCER INSTITUTE

Funding Acknowledgements

The authors wish to thank Liam Town, Kate Elder, Joanne Sutton, and Shellie Brown for breeding, genotyping, maintenance, and care of the mice used in this study. We thank Christopher Chan, Ricky Johnstone, and members of his group for providing the original Vk*MYC breeding pairs and helpful discussions. We thank Leesa Wockner for helpful advice concerning the statistical analysis of the data. L. Martinet and D.S. Ritchie were supported by a National Health and Medical Research Council (NH&MRC) of Australia Project grant (1044392). M.J. Smyth and L. Ferrari de Andrade were supported by a NH&MRC Australia Fellowship (628623) and Program Grant (1013667). L. Martinet was supported by the ARC cancer research foundation (PDF20140601127).