Journal article

Field evaluation of the establishment potential of wmelpop Wolbachia in Australia and Vietnam for dengue control

Hien Nguyen Tran, H Le Nguyen, Yen Nguyen Thu, Nam Vu Sinh, Duong Tran Nhu, TN Le, Mai Vien Quang, TC Bui, Tho Le Huu, Simon Kutcher, Tim P Hurst, TTH Duong, Jason AL Jeffery, Jonathan M Darbro, BH Kay, Inaki Iturbe-Ormaetxe, Jean Popovici, Brian L Montgomery, Andrew P Turley, Flora Zigterman Show all

PARASITES & VECTORS | BMC | Published : 2015


BACKGROUND: Introduced Wolbachia bacteria can influence the susceptibility of Aedes aegypti mosquitoes to arboviral infections as well as having detrimental effects on host fitness. Previous field trials demonstrated that the wMel strain of Wolbachia effectively and durably invades Ae. aegypti populations. Here we report on trials of a second strain, wMelPop-PGYP Wolbachia, in field sites in northern Australia (Machans Beach and Babinda) and central Vietnam (Tri Nguyen, Hon Mieu Island), each with contrasting natural Ae. aegypti densities. METHODS: Mosquitoes were released at the adult or pupal stages for different lengths of time at the sites depending on changes in Wolbachia frequency as a..

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University of Melbourne Researchers


Funding Acknowledgements

We thank D. Kien, K. Billington, A Callahan and N. Kenny for screening, F. Muzzi, G. Omodei, C. Omodei, M. Durkan and M. Greenfield for field and rearing support, D. Parkington and E. Thomson for mapping and data support and M. Turelli for discussions. The research was supported by the Foundation for the National Institutes of Health through the Grand Challenges in Global Health Initiative of the Bill and Melinda Gates Foundation and the National Health and Medical Research Council.