Journal article

Vertebral artery stenosis in the Basilar Artery International Cooperation Study (BASICS): prevalence and outcome

Annette Compter, Erik JRJ van der Hoeven, H Bart van der Worp, Jan Albert Vos, Christian Weimar, Christina M Rueckert, L Jaap Kappelle, Ale Algra, Wouter J Schonewille



We assessed the prevalence of vertebral artery (VA) stenosis or occlusion and its influence on outcome in patients with acute basilar artery occlusion (BAO). We studied 141 patients with acute BAO enrolled in the Basilar Artery International Cooperation Study (BASICS) registry of whom baseline CT angiography (CTA) of the intracranial VAs was available. In 72 patients an additional CTA of the extracranial VAs was available. Adjusted risk ratios (aRRs) for death and poor outcome, defined as a modified Rankin Scale score ≥4, were calculated with Poisson regression in relation to VA occlusion, VA occlusion or stenosis ≥50 %, and bilateral VA occlusion. Sixty-six of 141 (47 %) patients had uni- o..

View full abstract


Awarded by Dutch Heart Foundation

Funding Acknowledgements

The authors thank the BASICS study group and all health professionals from participating centres for their contribution to the BASICS registry [2]. AC, EJRJH, and HBW are supported by the Dutch Heart Foundation (2007/B045, 2010/B151, and 2010T075, respectively).