Journal article

Closure of a patent foramen ovale is associated with a decrease in prevalence of migraine: a prospective observational study

Justin GLM Luermans, Martijn C Post, Frederik Temmerman, Vincent Thijs, Wouter J Schonewille, HW Thijs Plokker, Maarten J Suttorp, Werner IHL Budts

Acta Cardiologica | TAYLOR & FRANCIS LTD | Published : 2008

Abstract

BACKGROUND: A causal relationship between migraine and a right-to-left shunt, due to a patent foramen ovale (PFO), has been suggested. In mainly retrospective studies, percutaneous closure of a PFO has been associated with a decrease in the prevalence of migraine. OBJECTIVE: In this prospective observational study we evaluated whether percutaneous closure of a PFO is associated with a decrease in the prevalence of migraine. METHODS: Between November 2003 and August 2005, we included 92 patients (age >16 years) who underwent a percutaneous closure of a symptomatic PFO, which was considered to be related to a paradoxical embolism.They received a headache questionnaire before and six months aft..

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