Journal article
What if stem cells turn into embryos in a dish?
MF Pera, G De Wert, W Dondorp, R Lovell-Badge, CL Mummery, M Munsie, PP Tam
Nature Methods | NATURE PUBLISHING GROUP | Published : 2015
DOI: 10.1038/nmeth.3586
Abstract
Recent studies show that pluripotent stem cells can undergo self-organized development in vitro into structures that mimic the body plan of the post-implantation embryo. Modeling human embryogenesis in a dish opens up new possibilities for the study of early development and developmental disorders, but it may also raise substantial ethical concerns.
Grants
Awarded by MRC
Awarded by Medical Research Council