Journal article

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

Dennis X Beringer, Fleur S Kleijwegt, Florian Wiede, Arno R van der Slik, Khai Lee Loh, Jan Petersen, Nadine L Dudek, Gaby Duinkerken, Sandra Laban, Antoinette Joosten, Julian P Vivian, Zhenjun Chen, Adam P Uldrich, Dale I Godfrey, James McCluskey, David A Price, Kristen J Radford, Anthony W Purcell, Tatjana Nikolic, Hugh H Reid Show all

Nature Immunology | NATURE PUBLISHING GROUP | Published : 2015

Grants

Awarded by Netherlands Organization for Scientific Research


Awarded by European Union


Funding Acknowledgements

We thank staff at the Australian synchrotron, the Leiden University Medical Center, the Monash Macromolecular Crystallization Facility, T. Beddoe, J. Teeler, C. van der Torren, S. Scally, M. Tran, S. Gras, K. Ladell, G. Dolton, R. Ayala-Perez and R. Berry for assistance. This work was supported by the Australian Research Council (ARC) and the National Health and Medical Research Council of Australia (NHMRC). A.P.U. is an ARC Future Fellow, D.I.G. is an NHMRC Senior Principal Research Fellow, D.A.P. is a Wellcome Trust Senior Investigator, K.J.R. is an NHMRC Career Development Fellow, A.W.P. is an NHMRC Senior Research Fellow, T.T. is an NHMRC Principal Research Fellow and K.J.R. is an NHMRC Australia Fellow. F.S.K., A.J. and B.O.R. are supported by the Netherlands Organization for Scientific Research (VICI 918.86.611), T.N. and S.L. are supported by the European Union 7th Framework Program (FP7/2007-2013) under Grant No. 241447 (Novel Immunotherapies for Type I Diabetes (NIAMIT)) and G.D. and A.R.v.d.S. are supported by the National Diabetes Expert Center funded by the Dutch Diabetes Research Foundation (DFN) and the Diabetes Research Netherlands (DON) Foundation.