Journal article
Association of physical activity and physical performance with tibial cartilage volume and bone area in young adults
B Antony, A Venn, F Cicuttini, L March, L Blizzard, T Dwyer, M Cross, G Jones, C Ding
Arthritis Research and Therapy | Published : 2015
Open access
Abstract
Introduction: Physical activity has been recommended to patients with knee osteoarthritis for improving their symptoms. However, it is still controversial if physical activity has effects on joint structures including cartilage volume. The aim of this study was to describe the associations between physical activity and performance measured 5 years prior and tibial cartilage volume and bone area in young adults. Methods: Subjects broadly representative of the Australian population (n = 328, aged 31-41 years, female 47.3 %) were selected from the Childhood Determinants of Adult Health study. They underwent T1-weighted fat-suppressed magnetic resonance imaging (MRI) scans of their knees. Tibial..
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Funding Acknowledgements
Special thanks go to the subjects who made this study possible. The roles of Liz O'Loughlin and Judy Hankin in collecting the data, Marita Dalton in managing the database, Rob Warren in processing the MR images and Petr Otahal in statistical analyses are gratefully acknowledged. C. Ding is a recipient of an ARC Future Fellowship, G. Jones is a recipient of an NHMRC Practitioner Fellowship, A. Venn is a recipient of a NHMRC Senior Research Fellowship, and L. Blizzard is a recipient of an NHMRC Career Development Fellowship. National Health and Medical Research Council of Australia funded this study and the funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Funding was provided by the National Health and Medical Research Council of Australia.