What's wrong with my mouse cage? Methodological considerations for modeling lifestyle factors and gene-environment interactions in mice

Gene-environment interactions in the regulation of neuroplasticity and cognitive function

This project will study the effects of different housing conditions on neuroplasticity-related cognitive function by combining an innovative..

TRANSGENERATIONAL IMPACTS OF PATERNAL STRESS ON OFFSPRING MENTAL HEALTH: EPIGENETIC MECHANISMS AND THERAPEUTIC INTERVENTIONS

We are following up the extraordinary, almost ‘Lamarckian’, discovery that environmental influences on fathers can affect their offspring vi..

GENE-ENVIRONMENT INTERACTIONS MODULATING COGNITION AND DEMENTIA IN HUNTINGTON’S DISEASE

We are investigating mechanisms whereby cognitive symptoms, culminating in dementia, occur in a fatal brain disease, Huntington’s. We will e..

Pathogenesis and therapeutic modulation of aggressive behaviour in a mouse model of autism spectrum disorder

This project focuses on understanding the causes of aggressive behaviour in mice that have a human gene mutation found in autism. Aggressive..