Journal article

Predictors of renal outcome in HIV-associated nephropathy

Frank A Post, Lucy J Campbell, Lisa Hamzah, Lisa Collins, Rachael Jones, Rizwan Siwani, Leann Johnson, Martin Fisher, Stephen G Holt, Sanjay Bhagani, Andrew H Frankel, Edmund Wilkins, Jonathan G Ainsworth, Nick Larbalestier, Derek C Macallan, Debasish Banerjee, Guy Baily, Raj C Thuraisingham, Paul Donohoe, Bruce M Hendry Show all

Clinical Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2008

Abstract

BACKGROUND: Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN) is an important cause of end-stage renal disease among African American patients. This study was performed to study the epidemiology of HIVAN in a predominantly black African population and the impact of highly active antiretroviral therapy and other factors on the development of end-stage renal disease. METHODS: We retrospectively identified all patients with HIVAN, defined by biopsy or strict clinical criteria, in 8 clinics in the United Kingdom. Baseline renal function, HIV parameters, renal pathological index of chronic damage, and responses to highly active antiretroviral therapy were analyzed, and factors ass..

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