Journal article
Predictors of renal outcome in HIV-associated nephropathy
Frank A Post, Lucy J Campbell, Lisa Hamzah, Lisa Collins, Rachael Jones, Rizwan Siwani, Leann Johnson, Martin Fisher, Stephen G Holt, Sanjay Bhagani, Andrew H Frankel, Edmund Wilkins, Jonathan G Ainsworth, Nick Larbalestier, Derek C Macallan, Debasish Banerjee, Guy Baily, Raj C Thuraisingham, Paul Donohoe, Bruce M Hendry Show all
Clinical Infectious Diseases | OXFORD UNIV PRESS INC | Published : 2008
DOI: 10.1086/529385
Abstract
BACKGROUND: Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN) is an important cause of end-stage renal disease among African American patients. This study was performed to study the epidemiology of HIVAN in a predominantly black African population and the impact of highly active antiretroviral therapy and other factors on the development of end-stage renal disease. METHODS: We retrospectively identified all patients with HIVAN, defined by biopsy or strict clinical criteria, in 8 clinics in the United Kingdom. Baseline renal function, HIV parameters, renal pathological index of chronic damage, and responses to highly active antiretroviral therapy were analyzed, and factors ass..
View full abstractGrants
Awarded by Medical Research Council