Journal article

Modified constraint-induced movement therapy or bimanual occupational therapy following injection of Botulinum toxin-A to improve bimanual performance in young children with hemiplegic cerebral palsy: a randomised controlled trial methods paper

Brian J Hoare, Christine Imms, Hyam Barry Rawicki, Leeanne Carey

BMC NEUROLOGY | BMC | Published : 2010

Abstract

BACKGROUND: Use of Botulinum toxin-A (BoNT-A) for treatment of upper limb spasticity in children with cerebral palsy has become routine clinical practice in many paediatric treatment centres worldwide. There is now high-level evidence that upper limb BoNT-A injection, in combination with occupational therapy, improves outcomes in children with cerebral palsy at both the body function/structure and activity level domains of the International Classification of Functioning, Disability and Health. Investigation is now required to establish what amount and specific type of occupational therapy will further enhance functional outcomes and prolong the beneficial effects of BoNT-A. METHODS/DESIGN: A..

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Funding Acknowledgements

The authors wish to express their gratitude to the children and their families who participated in the trial. They would also like to sincerely thank Trisnawati Tanumihardjo, Melanie Toy-Laing and Cate Clancy for administering the assessments and Lena Krumlinde-Sundholm, Marie Holmefur and Sue Greaves for scoring all the videos. Finally they would like to acknowledge the Allergan Australia and Southern Health and La Trobe University for supporting this research