Journal article

HCV treatment with pegylated interferon and ribavirin in patients with haemophilia and HIV/HCV co-infection

JT Denholm, EJ Wright, A Street, JJ Sasadeusz

Haemophilia | WILEY-BLACKWELL PUBLISHING, INC | Published : 2009

Abstract

Individuals with haemophilia are frequently infected with both human immunodeficiency virus (HIV) and hepatitis C virus (HCV); however, limited evidence is currently available regarding the efficacy of HCV treatment with pegylated interferon and ribavirin in this patient population. The aim of this study was to review HCV treatment outcomes in a cohort of patients with haemophilia and HIV/HCV co-infection. A retrospective, single centre review of 13 consecutive patients treated with pegylated interferon and ribavirin was performed. All patients were male with haemophilia A and a median age of 43 (range 27-62) at initiation of HCV therapy. Nine of 13 (69%) patients had genotype (gt1) 1 HCV (3..

View full abstract