Journal article

Untangling multi-gene families in plants by integrating proteomics into functional genomics

PG Sappl, JL Heazlewood, AH Millar

Phytochemistry | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2004

Abstract

The classification and study of gene families is emerging as a constructive tool for fast tracking the elucidation of gene function. A multitude of technologies can be employed to undertake this task including comparative genomics, gene expression studies, sub-cellular localisation studies and proteomic analysis. Here we focus on the growing role of proteomics in untangling gene families in model plant species. Proteomics can specifically identify the products of closely related genes, can determine their abundance, and coupled to affinity chromatography and sub-cellular fractionation studies, it can even provide location within cells and functional assessment of specific proteins. Furthermo..

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University of Melbourne Researchers