Journal article

Impact of an Ivermectin Mass Drug Administration on Scabies Prevalence in a Remote Australian Aboriginal Community

Therese M Kearns, Richard Speare, Allen C Cheng, James McCarthy, Jonathan R Carapetis, Deborah C Holt, Bart J Currie, Wendy Page, Jennifer Shield, Roslyn Gundjirryirr, Leanne Bundhala, Eddie Mulholland, Mark Chatfield, Ross M Andrews

PLoS Neglected Tropical Diseases | PUBLIC LIBRARY SCIENCE | Published : 2015


BACKGROUND: Scabies is endemic in many Aboriginal and Torres Strait Islander communities, with 69% of infants infected in the first year of life. We report the outcomes against scabies of two oral ivermectin mass drug administrations (MDAs) delivered 12 months apart in a remote Australian Aboriginal community. METHODS: Utilizing a before and after study design, we measured scabies prevalence through population census with sequential MDAs at baseline and month 12. Surveys at months 6 and 18 determined disease acquisition and treatment failures. Scabies infestations were diagnosed clinically with additional laboratory investigations for crusted scabies. Non-pregnant participants weighing ≥15 k..

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Awarded by National Health and Medical Research Council

Awarded by Cooperative Research Centre for Aboriginal Health

Funding Acknowledgements

This work was supported by National Health and Medical Research Council (GTN0605804 - TMK RS ACC JM JRC DCH BJC WP EM RMA & GNT0545239 - TMK); Cooperative Research Centre for Aboriginal Health (HS331 - RMA); and Northern Territory Research Innovation Board and Fund (Grant round 6-2008 - TMK) The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.