Impact of an Ivermectin Mass Drug Administration on Scabies Prevalence in a Remote Australian Aboriginal Community
Therese M Kearns, Richard Speare, Allen C Cheng, James McCarthy, Jonathan R Carapetis, Deborah C Holt, Bart J Currie, Wendy Page, Jennifer Shield, Roslyn Gundjirryirr, Leanne Bundhala, Eddie Mulholland, Mark Chatfield, Ross M Andrews
PLoS Neglected Tropical Diseases | PUBLIC LIBRARY SCIENCE | Published : 2015
BACKGROUND: Scabies is endemic in many Aboriginal and Torres Strait Islander communities, with 69% of infants infected in the first year of life. We report the outcomes against scabies of two oral ivermectin mass drug administrations (MDAs) delivered 12 months apart in a remote Australian Aboriginal community. METHODS: Utilizing a before and after study design, we measured scabies prevalence through population census with sequential MDAs at baseline and month 12. Surveys at months 6 and 18 determined disease acquisition and treatment failures. Scabies infestations were diagnosed clinically with additional laboratory investigations for crusted scabies. Non-pregnant participants weighing ≥15 k..View full abstract
Awarded by National Health and Medical Research Council
Awarded by Cooperative Research Centre for Aboriginal Health
This work was supported by National Health and Medical Research Council (GTN0605804 - TMK RS ACC JM JRC DCH BJC WP EM RMA & GNT0545239 - TMK) https://www.nhmrc.gov.au/; Cooperative Research Centre for Aboriginal Health (HS331 - RMA) http://www.lowitja.org.au/; and Northern Territory Research Innovation Board and Fund (Grant round 6-2008 - TMK) http://www.bulletpoint.com.au/northern-territory-research-and-innovation-fund/. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.