Journal article

Unusual Systemic Signs in a Dog with Sterile Neutrophilic-Macrophagic Lymphadenitis and Nodular Panniculitis

Julien RS Dandrieux, Katrin Timm, Petra J Roosje, Monika Welle, Judith Howard, Andreas Bruehschwein, Thierry Francey

Journal of the American Animal Hospital Association | AMER ANIMAL HOSPITAL ASSOC | Published : 2011


A 7 mo old female English springer spaniel was presented with diarrhea, vomiting, apathy, and hyperthermia. Further examinations revealed generalized lymphadenomegaly consistent with sterile neutrophilic-macrophagic lymphadenitis and pulmonary involvement. Subcutaneous nodules developed one day after presentation. Histology was consistent with sterile idiopathic nodular panniculitis and vasculitis. No infectious organism was isolated. The dog responded to prednisolone, but relapsed during medication tapering. Cyclosporine had to be added to control the disease. No further relapse had occurred 98 wk after the first presentation. This is an unusual presentation of a systemic sterile neutrophil..

View full abstract