Journal article

A feasibility study of X-ray phase-contrast mammographic tomography at the Imaging and Medical beamline of the Australian Synchrotron

Yakov I Nesterets, Timur E Gureyev, Sheridan C Mayo, Andrew W Stevenson, Darren Thompson, Jeremy MC Brown, Marcus J Kitchen, Konstantin M Pavlov, Darren Lockie, Francesco Brun, Giuliana Tromba

Journal of Synchrotron Radiation | INT UNION CRYSTALLOGRAPHY | Published : 2015

Abstract

Results are presented of a recent experiment at the Imaging and Medical beamline of the Australian Synchrotron intended to contribute to the implementation of low-dose high-sensitivity three-dimensional mammographic phase-contrast imaging, initially at synchrotrons and subsequently in hospitals and medical imaging clinics. The effect of such imaging parameters as X-ray energy, source size, detector resolution, sample-to-detector distance, scanning and data processing strategies in the case of propagation-based phase-contrast computed tomography (CT) have been tested, quantified, evaluated and optimized using a plastic phantom simulating relevant breast-tissue characteristics. Analysis of the..

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University of Melbourne Researchers

Grants

Awarded by ARC Australian Research Fellow


Funding Acknowledgements

We are grateful to Dr Nicola Sodini of Elettra-Sincrotrone Trieste for manufacturing the plastic phantom used in this study. We are also grateful to Ms Clare Scott and Dr Anton Maksimenko of the Australian Synchrotron for the assistance in preparation of the samples and for help in conducting the experiment, respectively. We are also grateful to Dr Jessica Lye of ARPANSA/RMIT for calculating the electron-loss correction factors for an ion chamber used in the experiment. KMP acknowledges financial support from the University of New England. MJK acknowledges funding from the Australian Research Council (ARC) and is an ARC Australian Research Fellow (DP110101941). This research was undertaken on the Imaging and Medical beamline at the Australian Synchrotron, Victoria, Australia.