HIV inhibits early signal transduction events triggered by CD16 cross-linking on NK cells, which are important for antibody-dependent cellular cytotoxicity
Gregor F Lichtfuss, Aislin C Meehan, Wan-Jung Cheng, Paul U Cameron, Sharon R Lewin, Suzanne M Crowe, Anthony Jaworowski
Journal of Leukocyte Biology | WILEY | Published : 2011
Awarded by National Health and Medical Research Council of Australia (NHMRC)
This study was funded through the National Health and Medical Research Council of Australia (NHMRC), project grant 543137. We thank Prof. Mark Hogarth for donating the anti-CD16 antibody, Cath Downs and the clinical research nursing staff of the Infectious Diseases Unit, The Alfred Hospital, for patient recruitment, and all participants and blood donors for the HiACT study. Further, we thank Dr. Marjon Navis, University of Melbourne, for constructive and critical discussion of the results.