Journal article

Phase 1 single dose studies to optimize the pharmacokinetics of DG17, a novel HIV-protease inhibitor pro-drug, using sodium bicarbonate and ritonavir

Catherine L Cherry, Jennifer F Hoy, James S Rowe, Henry Krum, John Mills, Sharon R Lewin

Current HIV Research | BENTHAM SCIENCE PUBL LTD | Published : 2008

DOI: 10.2174/157016208784324967

University of Melbourne Researchers

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Keywords

Life Sciences & Biomedicine
Hiv Infections
Hiv Protease Inhibitors
Cross-Over Studies
Drug Therapy, Combination
Gastric Acid
Pharmacoenhancement
Human-Immunodeficiency-Virus
Impact
Immunology
Protease Inhibitor
Healthy-Volunteers
Infected Patients
Haart
Humans
Male
Therapy
Sodium Bicarbonate
Ritonavir
Adolescent
Science & Technology
Virology
Middle Aged
Half-Life
Hiv
Prodrugs
Administration, Oral
Capsules
Infectious Diseases
Gastric Acid Neutralization
Adult
Drug Synergism
Metabolism
Combination
Area Under Curve
Adherence