CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells
Ervin E Kara, Duncan R McKenzie, Cameron R Bastow, Carly E Gregor, Kevin A Fenix, Abiodun D Ogunniyi, James C Paton, Matthias Mack, Diana R Pombal, Cyrill Seillet, Benedicte Dubois, Adrian Liston, Kelli PA MacDonald, Gabrielle T Belz, Mark J Smyth, Geoffrey R Hill, Iain Comerford, Shaun R McColl
Nature Communications | NATURE PUBLISHING GROUP | Published : 2015
Awarded by National Health and Medical Research Council (NHMRC)
We thank Professor Tracey Handel (University of California, La Jolla, USA) and the late Professor Ian Clark Lewis for recombinant chemokines and chemokine receptor antagonists; Dr Josef Ngyuen (Royal Adelaide Hospital, Adelaide, Australia) for mouse irradiation; Professor Brigitta Stockinger (Medical Research Council National Institute for Medical Research, UK) for B6.1117ac"Rosa26'YFP mice; Dr Christian Engwerda (QIMR Berghofer Medical Research Institute, Australia) for B6.Ccr2 - mice; Professor Bernhard Baune (University of Adelaide, Australia) for B6. Tnf- I, B6. Tnfrsfl a- I and B6. Tnfrsflb I - mice; Professor Carola Vinuesa (John Curtin School of Medical Research, Australia) for B6. Tcra- I - mice; Staff of the Laboratory Animal Services of the University of Adelaide for Animal Husbandry; and Staff of the Detmold Facility (IMVS, Australia) for some cell sorting experiments. This work was supported by funding held by S.R.M. and IC. from National Health and Medical Research Council (NH&MRC) Grant 1066781. IC. is supported by funds from Multiple Sclerosis Research Australia. M.J.S. is supported by an NH&MRC Research Fellowship (1078671). E.E.K. is supported by an Australian Postgraduate Award and the Norman and Patricia Polglase Scholarship.