Journal article

The impact of image resolution on computation of fractional flow reserve: coronary computed tomography angiography versus 3-dimensional quantitative coronary angiography

Lili Liu, Wenjie Yang, Yasuomi Nagahara, Yingguang Li, Saeb R Lamooki, Takashi Muramatsu, Pieter Kitslaar, Masayoshi Sarai, Yukio Ozaki, Peter Barlis, Fuhua Yan, Johan HC Reiber, Shengxian Tu

The International Journal of Cardiovascular Imaging | SPRINGER | Published : 2016


Calculation of fractional flow reserve (FFR) based on computational fluid dynamics (CFD) requires reconstruction of patient-specific coronary geometry and estimation of hyperemic flow rate. Coronary computed tomography angiography (CCTA) and invasive coronary angiography (ICA) are two dominating imaging modalities used for the geometrical reconstruction. Our aim was to investigate the impact of image resolution as inherently associated with these two imaging modalities on geometrical reconstruction and subsequent FFR calculation. Patients with mild or intermediate coronary stenoses who underwent both CCTA and ICA were included. CCTA images were acquired either by 320-row area detector CT or ..

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