Journal article

Perioperative renal failure in elderly patients

Johan Martensson, Rinaldo Bellomo

Current Opinion in Anaesthesiology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2015


PURPOSE OF REVIEW: To describe the epidemiology, pathophysiology, diagnosis and management of perioperative acute kidney injury (AKI) in elderly patients. RECENT FINDINGS: Elderly patients with a reduced renal reserve and multiple comorbidities have a higher risk of developing AKI after surgery. Postoperative AKI is diagnosed late and may even go undetected in immobilized elderly patients because of loss of muscle mass and reduced creatinine production. Panels of injury biomarkers could improve early risk stratification, but this approach needs further evaluation. The evidence for perioperative AKI prevention or treatment with renal vasodilators or remote ischaemic preconditioning is conflic..

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University of Melbourne Researchers