Magnesium status and magnesium therapy in critically ill patients: A systematic review

Abstract

Purpose: Magnesium is frequently measured and administered in general intensive care unit patients. However, magnesium status, its association with outcomes, and therapeutic utility in such patients are unclear. We performed a systematic review of the relevant literature to define current knowledge in this field. Materials and Methods: We searched MEDLINE, CENTRAL, and EMBASE from 1975 to July 2014 for adult English language articles excluding obstetric, non-intensive care unit based, and specific population (poisoning, cardiothoracic, and neurosurgery) studies. We identified articles on magnesium measurement, associations, and therapy. We calculated pooled effect estimates from reported adj..