Journal article

Acid-base balance during continuous veno-venous hemofiltration: The impact of severe hepatic failure

T Naka, R Bellomo, H Morimatsu, J Rocktaschel, L Wan, P Gow, P Angus

The International Journal of Artificial Organs | SAGE PUBLICATIONS LTD | Published : 2006


BACKGROUND: Continuous renal replacement therapy (CRRT) affects acid-base balance but the influence of severe hepatic failure (SHF) on this effect is unknown. AIM: To assess the effect of SHF on acid-base balance in patients receiving CVVH. DESIGN: Retrospective laboratory investigation. SUBJECTS: Forty patients with SHF and acute renal failure (ARF) treated with CVVH and 42 critically ill patients with severe ARF but no liver disease also treated with CVVH (controls). INTERVENTION: Retrieval of clinical and laboratory data from prospective unit and laboratory databases. METHODS: Quantitative acid-base status assessment using the Stewart-Figge methodology. Comparison of findings between the ..

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