Journal article

Cardiovascular effects of the nitric oxide synthase inhibitor N-G-methyl-L-arginine hydrochloride (546C88) in patients with septic shock: Results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002)

D Watson, R Grover, A Anzueto, J Lorente, M Smithies, R Bellomo, K Guntupalli, S Grossman, J Donaldson, JR Le Gall

Critical Care Medicine | LIPPINCOTT WILLIAMS & WILKINS | Published : 2004

DOI: 10.1097/01.CCM.0000104209.07273.FC

University of Melbourne Researchers

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95Web of Science
110Scopus

Keywords

Dysfunction
N-G-Methyl-L-Arginine Hydrochloride
Double-Blind Method
Follow-Up Studies
Dopamine
Severe Sepsis
Male
Pulmonary Circulation
Treatment Outcome
Model
Cardiac Output
Septic Shock
Shock, Septic
Clinical-Trial
Nitric Oxide Synthase Inhibitor
Severity of Illness Index
Vasoconstrictor Agents
Dose-Response Relationship, Drug
Sepsis Syndrome
Critical Care Medicine
Norepinephrine
Nitrate
Female
Intensive Care Units
Reference Values
Probability
Aged
Human
Adult
Science & Technology
Glaxo Wellcome International Septic Shock Study Group
Hemodynamics
Arginine
Risk Assessment
General & Internal Medicine
Middle Aged
Pressure
Invivo
Nitric Oxide Synthase
Omega-N-Methylarginine
Life Sciences & Biomedicine
Drug Administration Schedule
Placebo-Controlled Trial
Critical Care
Nitric Oxide
Randomized
Dobutamine
Humans
Survival Analysis
Cardiovascular System
Improves Survival