Review article: Renal support in critical illness
Sean M Bagshaw, Rinaldo Bellomo, Prasad Devarajan, Curtis Johnson, CJ Karvellas, D James Kutsiogiannis, Ravindra Mehta, Neesh Pannu, Adam Romanovsky, Geoffrey Sheinfeld, Samantha Taylor, Michael Zappitelli, RT Noel Gibney
Journal canadien d'anesthésie | SPRINGER | Published : 2010
PURPOSE: This review provides a focused and comprehensive update on established and emerging evidence in acute renal replacement therapy (RRT) for critically ill patients with acute kidney injury (AKI). PRINCIPAL FINDINGS: There have been considerable technological innovations in the methods and techniques for provision of extracorporeal RRT in critical illness. These have greatly expanded our capability to provide both renal and non-renal life-sustaining organ support for critically ill patients. Recent data suggest earlier initiation of RRT in AKI may confer an advantage for survival and renal recovery. Two large trials have recently shown no added benefit to augmented RRT dose delivery in..View full abstract
Dr. Bagshaw is supported by a Clinical Investigator Award from the Alberta Heritage Foundation for Medical Research. Dr. Zappitelli is supported by the Kidney Research Scientist Core Education and National Training program, the Fondation de Recherche en Sante du Quebec, and the Montreal Children's Hospital Research Institute.