Journal article

A prospective, multicenter study of the epidemiology, management, and outcome of severe acute renal failure in a "closed" ICU system

L Cole, R Bellomo, W Silvester, JH Reeves

American Journal of Respiratory and Critical Care Medicine | AMER THORACIC SOC | Published : 2000


The safety and effectiveness of "closed" intensive care units (ICUs) are highly controversial. The epidemiology and outcome of acute renal failure (ARF) requiring replacement therapy (severe ARF) within a "closed" ICU system are unknown. Accordingly, we performed a prospective 3-mo multicenter observational study of all Nephrology Units and ICUs in the State of Victoria (all "closed" ICUs), Australia, and focused on the epidemiology, treatment, and outcome of patients with severe ARF. We collected demographic, clinical, and outcome data using standardized case report forms. Nineteen ward patients and 116 adult ICU patients had severe ARF (13.4 cases/100, 000 adults/yr). Among the ICU patient..

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University of Melbourne Researchers