Journal article

Representation of people with aphasia in randomized controlled trials of acute stroke interventions

Myzoon Ali, Philip M Bath, Patrick D Lyden, J Bernhardt, Marian Brady



BACKGROUND: Aphasia affects up to a third of the stroke population and is associated with poor social participation and quality of life. Yet people with aphasia may be excluded from some types of stroke research due to challenges in informing, consenting, and conducting follow-up in this population. AIMS AND/OR HYPOTHESIS: We described the representation of those with aphasia in acute stroke clinical research, the level of inclusion across international trial sites, and whether there have been improvements in the inclusion of this population in recent clinical trials. METHODS: We conducted a retrospective analysis of clinical trial data from the Virtual International Stroke Trials Archive (V..

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Awarded by National Institute for Health Research

Awarded by Chief Scientist Office

Funding Acknowledgements

M. A., M. B., and the Nursing, Midwifery and Allied Health Professions Research Unit are funded by the Chief Scientist Office (CSO) Scottish Government's Health Directorate, Scotland. This work was funded as part of a CSO Post-Doctoral Fellowship Award. The views expressed here are those of the authors and not necessarily those of the CSO. VISTA is a not-for-profit collaboration of researchers from academia and commercial organizations. The VISTA Steering Committee members have each contributed to the organization of contributing trials, and where these have involved industry support, they have acknowledged that within the original publications.