Journal article

Relationship between serotonin and the Temperament and Character Inventory

AR Peirson, JW Heuchert, L Thomala, M Berk, H Plein, CR Cloninger

Psychiatry Research | ELSEVIER SCI IRELAND LTD | Published : 1999


The unified biosocial theory of personality, proposed by Cloninger, conceptualises personality as a combination of heritable, neurobiologically based traits (temperament dimensions), and traits reflecting sociocultural learning (character dimensions). The temperament dimensions are thought to be related to activity in specific central neurotransmitter systems. The relationship of the dimensions of the Temperament and Character Inventory, particularly harm avoidance (HA), and platelet 5-HT2 receptor sensitivity was investigated in a sample of undergraduate student volunteers (N = 49). Serotonin-receptor binding results in Ca2+ release from intracellular stores. The concentration of serotonin ..

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University of Melbourne Researchers