Acute neonatal respiratory failure
D Bohn, PA Dargaville, PG Davis, AA Hutchison, LS Owen
Pediatric and Neonatal Mechanical Ventilation: From Basics to Clinical Practice | Published : 2015
Acute respiratory failure requiring assisted ventilation is one of the most common reasons for admission to the neonatal intensive care unit. Respiratory failure is the inability to maintain either normal delivery of oxygen to the tissues or normal removal of carbon dioxide from the tissues. It occurs when there is an imbalance between the respiratory workload and ventilatory strength and endurance. Definitions are somewhat arbitrary but suggested laboratory criteria for respiratory failure include two or more of the following: PaCO2?>?60 mmHg, PaO2?50 mmHg or O2 saturation <80 % with an FiO2 of 1.0 and pH?7.25 (Wen et al. 2004).