The ON/OFF-response in retinopathy of prematurity subjects with myopia

Abstract

Retinopathy of prematurity (ROP) is often associated with myopia. Electrophysiological findings have shown that an imbalance of the ON- and OFF-response in subjects with ROP is associated with their refractive status. Nevertheless, the extent of these functional changes is still unclear. The aim of this study was to determine the extent of the ON- and OFF-response attenuation in ROP subjects with myopia. Fast and slow m-sequence multifocal electroretinogram were recorded on 14 eyes in 8 subjects with various degrees of myopia using the VERIS system. The spherical equivalent of refractive error ranged from -0.25 to -13.50 D. All ERG recordings were made using DTL electrodes with dilated pupil..