Journal article

OfftargetFinder: a web tool for species-specific RNAi design

RT Good, T Varghese, JF Golz, DA Russell, A Papanicolaou, O Edwards, C Robin

BIOINFORMATICS | OXFORD UNIV PRESS | Published : 2016

Abstract

MOTIVATION: RNA interference (RNAi) technology is being developed as a weapon for pest insect control. To maximize the specificity that such an approach affords we have developed a bioinformatic web tool that searches the ever-growing arthropod transcriptome databases so that pest-specific RNAi sequences can be identified. This will help technology developers finesse the design of RNAi sequences and suggests which non-target species should be assessed in the risk assessment process. AVAILABILITY AND IMPLEMENTATION: http://rnai.specifly.org CONTACT: crobin@unimelb.edu.au.