Journal article
Central adiposity, obesity during early adulthood, and pancreatic cancer mortality in a pooled analysis of cohort studies
JM Genkinger, CM Kitahara, L Bernstein, A Berrington de Gonzalez, M Brotzman, JW Elena, GG Giles, P Hartge, PN Singh, RZ Stolzenberg-Solomon, E Weiderpass, H-O Adami, KE Anderson, LE Beane-Freeman, JE Buring, GE Fraser, CS Fuchs, SM Gapstur, JM Gaziano, KJ Helzlsouer Show all
ANNALS OF ONCOLOGY | ELSEVIER | Published : 2015
Abstract
BACKGROUND: Body mass index (BMI), a measure of obesity typically assessed in middle age or later, is known to be positively associated with pancreatic cancer. However, little evidence exists regarding the influence of central adiposity, a high BMI during early adulthood, and weight gain after early adulthood on pancreatic cancer risk. DESIGN: We conducted a pooled analysis of individual-level data from 20 prospective cohort studies in the National Cancer Institute BMI and Mortality Cohort Consortium to examine the association of pancreatic cancer mortality with measures of central adiposity (e.g. waist circumference; n = 647 478; 1947 pancreatic cancer deaths), BMI during early adulthood (a..
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Grants
Awarded by NCI NIH HHS
Awarded by NHLBI NIH HHS
Awarded by NIA NIH HHS
Awarded by NIEHS NIH HHS
Awarded by PHS HHS
Awarded by NATIONAL CANCER INSTITUTE
Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Awarded by NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
Awarded by NATIONAL INSTITUTE ON AGING