Journal article
Aedes aegypti has spatially structured and seasonally stable populations in Yogyakarta, Indonesia
G Rašić, N Endersby-Harshman, W Tantowijoyo, A Goundar, V White, Q Yang, I Filipović, P Johnson, AA Hoffmann, E Arguni
Parasites and Vectors | Published : 2015
Abstract
Background: Dengue fever, the most prevalent global arboviral disease, represents an important public health problem in Indonesia. Control of dengue relies on the control of its main vector, the mosquito Aedes aegypti, yet nothing is known about the population history and genetic structure of this insect in Indonesia. Our aim was to assess the spatio-temporal population genetic structure of Ae. aegypti in Yogyakarta, a densely populated region on Java with common dengue outbreaks. Methods: We used multiple marker systems (microsatellites, nuclear and mitochondrial genome-wide single nucleotide polymorphisms generated via Restriction-site Associated DNA sequencing) to analyze 979 Ae. aegypti ..
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Funding Acknowledgements
This work is funded by the National Health and Medical Research Council, the Tahija Foundation and the Foundation for the National Institutes of Health through the Grand Challenges in Global Health Initiative of the Bill and Melinda Gates Foundation. Computational resources were provided by the NeCTAR Research Cloud at the University of Melbourne. The funders had no role in the study design, data collection, analyses and interpretation, or the manuscript writing.