Progesterone treatment reduces neuroinflammation, oxidative stress and brain damage and improves long-term outcomes in a rat model of repeated mild traumatic brain injury

Kyria M Webster; David K Wright; Mujun Sun; Bridgette D Semple; Ezgi Ozturk; Donald G Stein; Terence J O'Brien; Sandy R Shultz

Journal article

Progesterone treatment reduces neuroinflammation, oxidative stress and brain damage and improves long-term outcomes in a rat model of repeated mild traumatic brain injury

Kyria M Webster, David K Wright, Mujun Sun, Bridgette D Semple, Ezgi Ozturk, Donald G Stein, Terence J O'Brien, Sandy R Shultz

JOURNAL OF NEUROINFLAMMATION | BMC | Published : 2015

DOI: 10.1186/s12974-015-0457-7

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University of Melbourne Researchers

Bridgette Semple Author Medicine - Royal Melbourne Hospital

Nigel Jones Author Medicine - Royal Melbourne Hospital

Terry O'Brien Author Medicine - Royal Melbourne Hospital

Sandy Shultz Author Medicine - Royal Melbourne Hospital

Related Projects (1)

INVESTIGATING THE EFFECTS AND TREATMENT OF BRAIN CONCUSSIONS

Concussions are now recognized as a serious medical issue. There is particular concern for individuals who are at high risk of suffering con..

Grants

Awarded by National Health and Medical Research Council (NHMRC)

Funding Acknowledgements

We would like to thank Dr. Iqbal Sayeed (Emory University) for his contributions towards this project. This study was funded by a grant to SRS from the National Health and Medical Research Council (NHMRC # 1062653) and fellowships to SRS from the Canadian Institute of Health Research and NHMRC.