Journal article
Effect of age, family history of diabetes, and antipsychotic drug treatment on risk of diabetes in people with psychosis: A population-based cross-sectional study
DL Foley, A Mackinnon, VA Morgan, GF Watts, DJ Castle, A Waterreus, CA Galletly
Lancet Psychiatry | Published : 2015
Abstract
Background: Psychosis is associated with an increased risk of diabetes mellitus. A positive synergy between antipsychotic drug effects and a pre-existing liability to diabetes mellitus might explain the especially high relative risk of diabetes mellitus in young adults with psychosis. We aimed to assess the individual and joint effect of age, family history of diabetes mellitus, and currently prescribed antipsychotic drug treatment on risk for diabetes mellitus. Methods: In this study, we used data from the 2010 Australian National Survey of Psychosis-an observational study done at seven sites in five Australian states. We included data from 1155 people with psychosis aged 18-64 years who we..
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Funding Acknowledgements
This study is based on analysis of data collected in the framework of the 2010 Australian National Survey of Psychosis, which was funded by the Australian Government Department of Health and Ageing under a contract to The University of Western Australia. We acknowledge members of the 2010 Australian National Survey of Psychosis study group: V A Morgan (National Project Director), A Jablensky (Chief Scientifi Advisor), A Waterreus (National Project Coordinator), R Bush, V Carr, D J Castle, M Cohen, C A Galletly, C Harvey, B Hocking, A Mackinnon, P McGorry, J McGrath, A Neil, S Saw, and H Stain. We thank the hundreds of mental health professionals who participated in the preparation and undertaking of the survey and the many Australians with psychotic disorders who gave their time and whose responses form the basis of this publication. DLF and AM thank the Colonial Foundation (Melbourne, VIC, Australia) and the Australian Federal Government for their support of Orygen, The National Centre of Excellence in Youth Mental Health, and their support of their work on this manuscript.