Journal article
Hypertension, antihypertensive treatment and cancer incidence and mortality: A pooled collaborative analysis of 12 Australian and New Zealand cohorts
JL Harding, M Sooriyakumaran, KJ Anstey, R Adams, B Balkau, S Brennan-Olsen, T Briffa, TME Davis, WA Davis, A Dobson, GG Giles, J Grant, R Huxley, M Knuiman, M Luszcz, P Mitchell, JA Pasco, CM Reid, D Simmons, LA Simons Show all
Journal of Hypertension | LIPPINCOTT WILLIAMS & WILKINS | Published : 2016
Abstract
Background: Observational studies examining associations between hypertension and cancer are inconsistent. We explored the association of hypertension, graded hypertension and antihypertensive treatment with cancer incidence and mortality. Method: Eighty-six thousand five hundred and ninety-three participants from the Australian and New Zealand Diabetes and Cancer Collaboration were linked to the National Death Index and Australian Cancer Database. Cox proportional hazards models estimated hazard ratios and 95% confidence intervals (95% CI) for the association of treated and untreated hypertension with cancer incidence and mortality. Results: Over a median follow-up of 15.1 years, 12 070 inc..
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Awarded by National Health and Medical Research Council (NHMRC)
Funding Acknowledgements
This work is funded by a National Health and Medical Research Council (NHMRC grant APP1002663) and Australian Government Department of Health. The work is supported, in part, by the Victorian Operational Infrastructure Scheme.