Repeated Blood Pressure Measurements in Childhood in Prediction of Hypertension in Adulthood
Mervi Oikonen, Joel Nuotio, Costan G Magnussen, Jorma SA Viikari, Leena Taittonen, Tomi Laitinen, Nina Hutri-Kahonen, Eero Jokinen, Antti Jula, Michael Cheung, Matthew A Sabin, Stephen R Daniels, Olli T Raitakari, Markus Juonala
Hypertension | LIPPINCOTT WILLIAMS & WILKINS | Published : 2016
Hypertension may be predicted from childhood risk factors. Repeated observations of abnormal blood pressure in childhood may enhance prediction of hypertension and subclinical atherosclerosis in adulthood compared with a single observation. Participants (1927, 54% women) from the Cardiovascular Risk in Young Finns Study had systolic and diastolic blood pressure measurements performed when aged 3 to 24 years. Childhood/youth abnormal blood pressure was defined as above 90th or 95th percentile. After a 21- to 31-year follow-up, at the age of 30 to 45 years, hypertension (>140/90 mm Hg or antihypertensive medication) prevalence was found to be 19%. Carotid intima-media thickness was examined, a..View full abstract
Awarded by National Health and Medical Research Council
The Study has been financially supported by the Academy of Finland, the Social Insurance Institution of Finland, Kuopio, Tampere and Turku University Hospital Medical Funds, Orion-Farmos Research Foundation, Juho Vainio Foundation, Paavo Nurmi Foundation, Paulo Foundation, Maud Kuistila Foundation, Finnish Medical Foundation, Finnish Foundation of Cardiovascular Research, Finnish Cultural Foundation, the Sigrid Juselius Foundation, Yrjo Jahnsson Foundation, Tampere Tuberculosis Foundation and Emil Aaltonen Foundation. C.G. Magnussen is supported through a National Health and Medical Research Council Early Career Fellowship (APP1037559).