Journal article
Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: A randomised controlled trial
A Pipingas, A Sinclair, KD Croft, AS Januszewski, AJ Jenkins, TA Mori, R Cockerell, NA Grima, C Stough, A Scholey, SP Myers, A Sali, MP Pase
Journal of Functional Foods | Published : 2015
Abstract
The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol.
Grants
Funding Acknowledgements
We are grateful to the study participants. During the study, MPP was funded by a Menzies Foundation Scholarship in Allied Health Science.