Optically tunable hydrogel biosensor material
Teck-Choon Ayi, Jill Mei-Mei Tong, Peter Vee-Sin Lee, PJ Gardner (ed.), AW Fountain (ed.)
CHEMICAL AND BIOLOGICAL SENSING VII | SPIE-INT SOC OPTICAL ENGINEERING | Published : 2006
Colloidal crystal hydrogels with tunable optical properties are useful materials to construct thermoresponsive tunable photonic crystals' and optical switch that responds in nanoseconds2. We report here instead, the fabrication of optically tunable colloidal crystal hydrogel material that can also behave as biosensors, responding to the presence of antigens or antibodies. Optically tunable hydrogel material was fabricated from submicron sized, thermoresponsive poly-N-isopropyl acrylamide (pNIPAM) particles and pNIPAM-co-acrylic acid (pNIPAM-AA) copolymer particles. The color of this translucent hydrogel material can be tuned from blue to green to red by changing the concentration of pNIPAM p..View full abstract
We are indebted to DRD-DSTA and DMERI-DSO for funding the research described in this paper. We thanked Dr. Yang Yi Yan from the Institute of Bioengineering and Nanotechnology, Singapore, for helping us with regards to the 90Plus Particle size Analyzer, and Dr. Janaky Narayanan and Mr Teo Hoon Hwee from the Department of Physics, National University of Singapore, for their advice and help with the Bl-200SM Research Goniometer System.