Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity
Prabhakara R Nagareddy, Michael Kraakman, Seth L Masters, Roslynn A Stirzaker, Darren J Gorman, Ryan W Grant, Dragana Dragoljevic, Eun Shil Hong, Ahmed Abdel-Latif, Susan S Smyth, Sung Hee Choi, Judith Korner, Karin E Bornfeldt, Edward A Fisher, Vishwa Deep Dixit, Alan R Tall, Ira J Goldberg, Andrew J Murphy
Cell Metabolism | CELL PRESS | Published : 2014
Awarded by NIH
Awarded by National Institute of Diabetes and Digestive and Kidney Diseases
Awarded by American Heart Association
Awarded by National Health and Medical Research Council
We thank Bristol-Myers Squibb for the SGLT2 inhibitor. We thank Melinda Coughlan (Baker IDI) for the db/db mice and the Flow Cytometry and Imaging facilities at Columbia University. This project was funded by grants from the NIH (U01-HL087945 and DK095684 to I.J.G. and E. A. F.; HL45095 to I.J.G.; HL87123 to A. R. T.; P01HL092969, R01HL097365, and R01HL062887 to K. E. B.; and AG031797, AG043608, AI105097, and DK090556 to V. D. D.), grants from the National Institute of Diabetes and Digestive and Kidney Diseases (RO1DK072011 to J.K. and UL1TR000117 and P20 GM103527 to A. A.-L.), and a Pilot and Feasibility Award from the Diabetes Complications Consortium (to I.J.G.). R. W. G. was supported by NIH T32 training grant DK064584-10. P.R.N. was supported by a postdoctoral fellowship from the Canadian Institutes of Health Research and a Pathway to Independence Award from the NIH (1K99HL122505). A.J.M. was supported in part by a postdoctoral fellowship from the American Heart Association (12POST11890019), a Viertel award from Diabetes Australia Research Trust Australia, and a National Health and Medical Research Council program grant (APP10363652). The authors acknowledge support from BMS Pharmaceutical Company.