Succinate is an inflammatory signal that induces IL-1 beta through HIF-1 alpha
GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, AF McGettrick, G Goel, C Frezza, NJ Bernard, B Kelly, NH Foley, L Zheng, A Gardet, Z Tong, SS Jany, SC Corr, M Haneklaus, BE Caffrey, K Pierce, S Walmsley, FC Beasley Show all
Nature | NATURE PUBLISHING GROUP | Published : 2013
Awarded by Medical Research Council
We thank the European Research Council, Science Foundation Ireland, the Health Research Board, European Union FP7 programme 'TIMER', Wellcome Trust, National Institutes of Health, Helmsley Trust, Nestle Research Centre, VESKI, The Duquesne University Hunkele Dreaded Disease Award, The Interleukin Foundation and the National Health and Medical Research Council for funding. We also thank R. Thompson for assistance with Hif1a<SUP>-/-</SUP> mice and M. Murphy for discussions.