Journal article

Warts Opens Up for Activation

Samuel A Manning, Kieran F Harvey

DEVELOPMENTAL CELL | CELL PRESS | Published : 2015

Abstract

Warts is the central effector kinase of the Hippo growth-control pathway. In this issue of Developmental Cell, by assessing Warts conformation in vivo, Vrabioiu and Struhl (2015) report that the Mob family protein Mats regulates Warts activity allosterically, independent of phosphorylation by Hippo.