Journal article

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Alexander Gusev, S Hong Lee, Gosia Trynka, Hilary Finucane, Bjarni J Vilhjalmsson, Han Xu, Chongzhi Zang, Stephan Ripke, Brendan Bulik-Sullivan, Eli Stahl, Anna K Kaehler, Christina M Hultman, Shaun M Purcell, Steven A McCarroll, Mark Daly, Bogdan Pasaniuc, Patrick F Sullivan, Benjamin M Neale, Naomi R Wray, Soumya Raychaudhuri Show all

The American Journal of Human Genetics | CELL PRESS | Published : 2014

Grants

Awarded by Wellcome Trust


Awarded by NIH


Awarded by NIH fellowship


Awarded by Australian Research Council


Awarded by National Health and Medical Research Council


Awarded by Lundbeck Foundation


Awarded by Medical Research Council


Awarded by Chief Scientist Office


Awarded by NATIONAL HUMAN GENOME RESEARCH INSTITUTE


Awarded by NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES


Awarded by NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES


Awarded by NATIONAL INSTITUTE OF MENTAL HEALTH


Funding Acknowledgements

This study made use of data generated by the Wellcome Trust Case Control Consortium (WTCCC) and the Wellcome Trust Sanger Institute. A full list of the investigators who contributed to the generation of the WTCCC data is available at www.wtccc.org.uk. Funding for the WTCCC project was provided by the Wellcome Trust under award 076113. We thank Manolis Kellis, Abhishek Sarkar, Joe Pickrell, X. Shirley Liu, Nick Patterson, Sara Lindstrom, Peter Kraft, and Shamil Sunyaev for helpful discussions and Amy Williams for assistance with HApI-UR. This research was funded by NIH grants R01 MH101244, R03 HG006731, and 1U01HG0070033, the Doris Duke Clinical Scientist Development Award, and NIH fellowship F32 GM106584. G.T. was supported by the Rubicon grant from the Netherlands Organization for Scientific Research. H.F. was supported by the Fannie and John Hertz Foundation. We also acknowledge grant funding from the Australian Research Council (DE130100614 and FT0991360) and the National Health and Medical Research Council (613602 and 1050218).