Journal article

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15

Rebecca B Delconte, Wei Shi, Priyanka Sathe, Takashi Ushiki, Cyril Seillet, Martina Minnich, Tatiana B Kolesnik, Lucille C Rankin, Lisa A Mielke, Jian-Guo Zhang, Meinrad Busslinger, Mark J Smyth, Dana S Hutchinson, Stephen L Nutt, Sandra E Nicholson, Warren S Alexander, Lynn M Corcoran, Eric Vivier, Gabrielle T Belz, Sebastian Carotta Show all

Immunity | CELL PRESS | Published : 2016

Grants

Awarded by National Health and Medical Research Council (NH&MRC) of Australia


Awarded by National Health and Medical Research Council of Australia


Awarded by ERC Advanced Grant (Lymphocyte Control) from the European Community's Seventh Framework Program



Funding Acknowledgements

We wish to thank Tobias Kratina, Tania Camilleri, Pradnya Gangatirkar, Hesham Abdulla, Cathy Quillici, and Mary Camilleri for technical assistance and Andreas Strasser, Ross Dickins, and Philippe Bouillet for reagents and helpful discussion. We thank the staff of the WEHI Animal Services, monoclonal antibody facility, the flow cytometry facility, and Clinical Translational Centre. This work is supported by program and project grants from the National Health and Medical Research Council (NH&MRC) of Australia (1027472 to S.C., N.D.H., and G.T.B.; 1047903 to G.T.B. and L.A.M.; 1016647 to J.-G.Z., S.E.N., and W.S.A.; 1049407, 1066770, 1057852 to N.D.H.). This work is supported by fellowships from the National Health and Medical Research Council of Australia (GNT0461276 to N.D.H.; 1058344 to W.S.A.; 545952 to D.S.H.; Dora Lush Training Scholarship to L.C.R.), the Australian Research Council (S.C., G.T.B., S.L.N.), Australia Fellowship (628623) to M.J.S., Cancer Australia (L.A.M.), and The Menzies Foundation (N.D.H.). R.B.D. is supported by a Leukaemia Foundation scholarship. The E.V. lab is supported by the European Research Council (THINK Advanced Grant) and by institutional grants from INSERM, CNRS, and Aix Marseille to CIML. E.V. is a scholar of the Institut Universitaire de France. The M.B. group was supported by Boehringer Ingelheim and an ERC Advanced Grant (291740 - Lymphocyte Control) from the European Community's Seventh Framework Program. This study was made possible through Victorian State Government Operational Infrastructure Support and Australian Government NHMRC Independent Research Institute Infrastructure Support scheme.