Journal article
Long-term effect of high-dose supplementation with DHA on visual function at school age in children born at < 33 wk gestational age: Results from a follow-up of a randomized controlled trial
CS Molloy, S Stokes, M Makrides, CT Collins, PJ Anderson, LW Doyle
American Journal of Clinical Nutrition | Published : 2016
Abstract
Background: Children born preterm are at risk of visual-processing impairments. Several lines of evidence have contributed to the rationale that docosahexaenoic acid (DHA) supplementation of preterm infants may improve outcomes in visual processing. Objective: The aim was to determine whether at 7 y of age children who were born very preterm and who received a high-DHA diet have better visual-processing outcomes than do infants fed a standard-DHA diet. Design: This was a follow-up study in a subgroup of children from a randomized controlled trial. Infants were randomly assigned to milk containing a higher concentration of DHA (1% of total fatty acids; high-DHA group) or a standard amount of ..
View full abstractGrants
Awarded by National Health and Medical Research Council (NHIMRC), Australia
Awarded by Center of Clinical Research Excellence in Newborn Medicine grant
Awarded by NHMRC
Awarded by National Health and Medical Research Council of Australia
Funding Acknowledgements
Supported by the National Health and Medical Research Council (NHIMRC), Australia, 5-y project grant (508003) and the Center of Clinical Research Excellence in Newborn Medicine grant (546519); Mead Johnson Nutrition; and the Victorian Government's Operational Infrastructure Support Program. NHMRC fellowships support PJA (Senior Research Fellow APP628371 and 1081288) and MM (Principal Research Fellow APP1061704). CTC is supported through an MS McLeod Research Fellowship (MS McLeod Research Fund, Women's and Children's Hospital Research Foundation). Treatment and placebo capsules for the original trial were donated by Clover Corporation, and infant formula was donated by Mead Johnson Nutrition and Nutricia Australasia.