The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP4 receptor activity

Nitin A Patil; Ross AD Bathgate; Martina Kocan; Sheng Yu Ang; Julien Tailhades; Frances Separovic; Roger Summers; Johannes Grosse; Richard A Hughes; John D Wade; Mohammed Akhter Hossain

Journal article

The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP4 receptor activity

Nitin A Patil, Ross AD Bathgate, Martina Kocan, Sheng Yu Ang, Julien Tailhades, Frances Separovic, Roger Summers, Johannes Grosse, Richard A Hughes, John D Wade, Mohammed Akhter Hossain

AMINO ACIDS | SPRINGER WIEN | Published : 2016

DOI: 10.1007/s00726-015-2144-5

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University of Melbourne Researchers

Frances Separovic Author Chemistry

Akhter Hossain Author Florey Department of Neuroscience and Mental Health

Ross Bathgate Author Florey Department of Neuroscience and Mental Health

John Wade Author Florey Department of Neuroscience and Mental Health

Martina Kocan Author Florey Department of Neuroscience and Mental Health

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Funding Acknowledgements

This research was partly funded by NHMRC (Australia) project grants ( 1023321, 1065481, 1023078) to M. A. H, R. A. D. B and J. D. W and ARC linkage grant (LP120100654) to R. A. H. We are grateful to Tania Ferraro and Sharon Layfield for assistance with biochemical assays. During these studies, M. A. H. was the recipient of Florey Foundation Fellowships. R. A. D. B. is an NHMRC Senior Research Fellow, and J. D. W. is an NHMRC Principal Research Fellow. Studies at the FINMH were supported by the Victorian Government's Operational Infrastructure Support Program.